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Chromo shadow domain : ウィキペディア英語版 | Chromo shadow domain
In molecular biology, the chromo shadow domain is a protein domain which is distantly related to the chromodomain. It is always found in association with a chromodomain. Proteins containing a chromo shadow domain include ''Drosophila'' and human heterochromatin protein Su(var)205 (HP1); and mammalian modifier 1 and modifier 2. Chromoshadow domains self aggregate, bringing together the nucleosomes to which their proteins are bound and thus condense the chromatin region they are associated with. Condensed chromatin is not able to be transcribed as the transcription factors and enzymes are not able to access to DNA sequence in this form. Hence chromoshadow domain containing proteins repress gene transcription.〔 〕 ==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Chromo shadow domain」の詳細全文を読む
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